Vol. 2, Issue 6
Nov - Dec 2004

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Using STELLA to Teach Immunology

Sarah Strack
Champlain Valley Union High School
Hinesburg, Vermont

Sarah Strack
Environmental Systems Teacher, 13 years
Champlain Valley Union High School
Hinesburg, VT

E-mail: Sarah@cvuhs.org

As society changes, so does the next generation's exposure to the variety and complexity of diseases in the world. The anthrax scares of 2001 alerted students across our nation to how an individual can become infected with a disease, but also led to questions concerning why everyone did not become infected. Advertisements bombard our students, filling their minds with small bits of information regarding their body's need for prescription drugs, but this information is disconnected from an understanding of how an individual's immune system works or how a disease is contracted. As a result, our students are forming opinions based on marketing techniques and not scientific facts or research.

To address this issue, Champlain Valley Union High School in Hinesburg, VT began offering a semester long class geared mainly towards sophomores entitled Introduction to Human Biology. The course was designed around Vermont Framework of Standards 7.14 and seeks to "introduce students to heredity, body systems, and individual development." The course is broken into units based on the 10 body systems and the study of human genetics. When designing the course, department faculty reviewed several textbooks and ultimately decided upon Modern Biology by Towle, which is also used in the ninth grade program.

As one of the designers of the course, I use the book quite extensively in the classroom, helping students decipher the language of biology as they learn about their body systems. However, I have become increasing critical of the chapter on the Immune System after using it in several semesters worth of classes. As a result of the book's limitations, I began pondering new methods to use when teaching the immune system. To that end I developed an action research project aimed at creating and assessing a new immunology unit which integrates systems thinking via STELLA computer modeling in order to help students think holistically about disease. Through systems thinking and STELLA I could give my students a broad overview of how their immune system operates and how it relates to systemic issues such as communicable diseases and vaccinations.

My revised immunology unit consisted of the following activities: a two part in-class lecture on the human immune response that consisted of traditional note taking and the use of two STELLA models shown to the students via a projector and a student handout.(Part one of my human immune response lecture consisted of the Nonspecific Immune Defenses and the start of the Specific Immune Responses, ending with B and T cell production. Part two picked up with B and T cell production using a STELLA model, then discussed the cell mediated and humoral immune responses using first a STELLA model and then traditional note taking.) A second lecture followed discussing how diseases are spread through a population, transmission rates for diseases, and how a person can become naturally immune to a disease and acquire immunity through exposure and vaccinations.

Two lab activities followed the lectures. The first was a communicable disease lab entitled NERDS: New England Regional Disease Syndrome. This imaginary disease spread through our class using one infected individual, handshakes, and transmission rate probabilities. From the lab, the class was able to create a STELLA model depicting relationships between different variables as the disease spread through the class. The second lab examined communicable diseases and vaccinations in a population. After reviewing the STELLA model from the previous lab with the class, laptop computers were given to pairs of students with a pre-built model. The flight simulator allowed students to change the data for each variable finding "tipping points" for different variables the simulation.

I evaluated the success of the unit based on three surveys. While I was unable to find any relevant conclusions when comparing the pre-unit and post-unit surveys, I did receive very interesting feedback from the overall unit questionnaire. Students had strong reactions to about the using and understanding of the STELLA model in the lecture. The majority of the students felt the models added to the lecture notes, but preferred when I gave note first and then showed the model. This allowed them to make direct connections to the model structure. When I showed the model first and then gave notes, one student remarked in their survey, "I had forgotten all the pathways by the time I got all the notes written down." Based on their feedback I will utilize the storytelling feature next year.

Overall I was very pleased with the outcome of this unit. Students were engaged in the activities, and the models improved their understanding of the human immune system. The students' feedback is invaluable as I modify this unit and plan for the implementation of Systems Thinking and STELLA into other units.